Project Description

What is Sanguinol ®?
Sanguinol ® is a natural, green herbal feed additive and high-performance AGP alternative, formulated with Macleaya cordata extract (also found in other products like Sangrovit ®*) as its core ingredient, which delivers standardized sanguinarine and chelerythrine — bioactive benzophenanthridine alkaloids (QBAs) renowned for their antimicrobial, anti-inflammatory, and immune-modulatory properties.
Note: Sangrovit ® is a registered trademark of a Germany-based company and is not affiliated with this product.


Stress Resilience
• Reduces cortisol/corticosterone levels during critical periods (weaning, transport, heat stress)
• Lowers oxidative stress and inflammation


Performance Enhancement

Poultry: Weight gain, improved carcass quality

Poultry: FCR

Swine: Post-weaning diarrhea

Swine: Feed efficiency

Ruminants: Milk yield, immune function

Aquaculture: Survival rates, feed utilization


Gut Health
• Modulates gut microbiota, strengthening intestinal barrier function
• Reduces pathogenic bacterial load (e.g., E. coli, Clostridium)


Mechanism of Action

Inhibits NF-κB pathway → reduces inflammation
Regulates HPA-axis → lowers stress hormones
Enhances antioxidant capacity → (↑ SOD, GSH-Px activity)

Safety & Compliance
100% plant-based      antibiotic-free      Zero withdrawal       non-GMO
For Which Species?
  • Swine: In weaned piglets, growing pigs, late gestation and lactating sows, it has the effects of promoting growth, anti-stress, and improving intestinal health.
  • Poultry: Sanguinol can increase feed intake and weight gain of broilers, reduce feed-to-meat ratio; improve intestinal health, improve diet digestibility, reduce overfeeding; enhance body resistance, prevent disease infection; improve egg production rate, reduce mortality rate. It can also prevent and treat Salmonella and Clostridium perfringens infections in broilers. Alaeldein M. Abuda-bos and other studies reported that benzophenanthridine alkaloids from Sanguinol could reduce the intestinal tract damage of broiler chickens challenged with Salmonella typhimurium, promote broiler’s growth performance and gut health. G. D. Xue et al. reported that the alkaloids extracted from Sanguinol can promote the recovery of growth performance and meat production performance of broiler chickens challenged with Clostridium perfringens, and lower the score for lesions of duodenum, jejunum and ileum in challenged broiler chickens. On-site farm in Duhok University, a flock was infected by IB and avian flu, adding Sanguinol WS reduced mortality rate significantly at a dosage of 120g/1000L water.
  • Ruminants: Prevention of Cryptosporidia, Mastitis and metritis.
  • Aquaculture: It can kill many parasites that threaten the production of aquatic animals, such as Schistosoma japonicum, ringworm and melon worm, and it can promote growth, improve immunity, improve health and other aquatic animals, such as perch, red tilapia, koi, carp, and South American shrimp. On red tilapia (Oreochromis niloticus), compared to the control group, the allochthonous lactic acid bacteria (LAB) populations were lower (Mark D. Rawling et al., 2009).
Sanguinol can be mixed with premixes, feeds, minerals, milk replacers and drinking water.