COMPOSITION:

Each 1 kg contain:

Diclazuril 50 g

Excipients   950 g

Pharmacological action

Diclazuril is a chemical anticoccidial, a benzeneacetonitrile derivative – synthetic compound of the triazinone family. Diclazuril is has a mode of action completely different from the existing ionophores and chemicals, available on the market. According to the anticoccidial properties of triazinones, diclazuril is active against intracellular development stages of coccidia, namely during schizogony and gametogony. After diclurazil treatment, the first- and second-generation schizonts show extensive degenerative changes which are characterised by the loss of internal structure, the appearance of many intracytoplasmic vacuoles and incomplete merogony. Ultrastructural findings indicate that diclazuril treatment primarily affects the normal differentiation of the respective endogenous stages during parasite development. This leads to complete degeneration of schizonts and gamonts.

Indications

As an aid in the prevention of coccidiosis caused by Eimeria acervulina, E. brunetti, E. maxima, E. mitis, E. praecox, E. necatrix and E. tenella in broiler chickens and chickens reared for laying. As an aid in the prevention of coccidiosis caused by Eimeria adenoeides, E. meleagrimitis and E. gallopavonis in turkeys for fattening. As an aid in the prevention of coccidiosis caused by Eimeria irresidua, Eimeria media, Eimeria flavescens, Eimeria intestinalis, Eimeria perforans, Eimeria piriformis, Eimeria stiedai, Eimeria magna, E.exigua and E.coecicola in rabbits for fattening and breeding. For the prevention of E. numidae and E. grenieri in guinea fowls.

Contraindications

No contraindications are known under correct usage of the product.

Target species

Broilers, chickens reared for laying, turkeys for fattening, rabbits for fattening and breeding and guinea fowls.

Dosage                                                   Diclazuril (ppm)         Diclazuril 5% premix (g/ton)    Maximum age (weeks)       Withdrawal period (days)

Broilers                                                           1                                               20                                           –                                       0
Chickens reared for laying                              1                                               20                                         16                                      –
Turkeys for fattening                                       1                                               20                                         12                                      0
Rabbits Fatteners-Breeders                           1                                               20                                           –                                      1 day
Guinea Fowl                                                   1                                               20                                           –                                        0

Mixing instruction:

Ensure uniform dispersion of enramycin premix in feed by method of multi-stage mixing. Or add to combined feed through a commercially produced vitamin  and mineral premix.

Storage

Store under dry conditions below 25ºC.

Expiry date is 2 (two) years after date of manufacture.

Packing

25 kg bags: Inner lining is made of polyethylene; outer layer is made of 3-ply paper.