Project Description

Tilmicosin 20%

For the treatment and prevention of respiratory infections associated with Mycoplasma hyopneumoniae, Pasteurella multocida and Actinobacillus pleuropneumoniae.

For the treatment and prevention of respiratory infections in poultry flocks associated with Mycoplasma gallisepticum and Mycoplasma synoviae

COMPOSITION:

Each 1 kg contain:

Tilmicosin  200 g

Excipients   800 g

 

PHARMACOLOGICAL ACTION

Tilmicosin, (20-deoxo-20-(3,5-dimethylpiperidin-1-yl)-desmycosin) is chemically modified longacting macrolide antibiotic applied in the veterinary medicine. It is active mainly against Gram-positive, some Gram-negative microorganisms (Streptococci, Staphylococci, Pasteurella spp.) and Mycoplasmas spp., etc. Applied orally in pigs, tilmicosin reaches maximum blood levels after 2 hours and maintains high therapeutic concentrations in the target tissues. It is concentrated in the lungs, penetrating intracellularly in the alveolar macrophages. It is eliminated mainly through feces and urine. Tilmicosin induces no teratogenic and embryotoxic effect.

INDICATIONS

For prophylactics (metaphylactics) and treatment of bacterial respiratory diseases caused by Mycoplasma hyopneumoniae (Enzootic Pneumonia); Actonobacillus pleuropneumoniae (Actinobacillus pleuropneumoniae); Haemophilus parasuis (Haemophilus pneumonia or Glasser’s disease); Pasteurella multocida (Pasteurellosis); Bordetella bronchiseptica and other microorganisms sensitive to tilmicosin. Secondary bacterial infections, associated with Porcine Reproductive and Respiratory Syndrome (PRRS) and circovirus Pneumonia (Post-Weaning Multisystemic Wasting Syndrome – PMWS and Porcine Dermatitis and Nephropathy Syndrome – PDNS). Bacterial infections of the alimentary tract, caused by Brachispira hyodysenteriae (classic Dysentery); Lawsonia intracellularis (proliferative and hemorrhagic ileitis); Brachispira pilosicoli (colon Spirochetosis); Staphylococcus spp. and Streptococcus spp.; in stress conditions for prevention (metaphylactics) after weaning, moving, regrouping and transportation of pigs.

For the treatment and prevention of respiratory infections in poultry flocks associated with Mycoplasma gallisepticum and Mycoplasma synoviae.

CONTRAINDICATIONS

Not established.

MODE OF ADMINISTRATION

Orally, well homogenized into feed. In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order: up to 10 kg feed; up to 100 kg feed; and up to 1000 kg feed.

Dosage

Pig:

Prevention/ Control (for the risk period, typically for 21 days, recommended to start 7 days prior to an expected disease outbreak)        1kg/ton feed
Treatment (for a period of 10-15 days)                          1-2kg/ton feed

Poultry:

Prevention/Control respiratory infections in poultry flocks associated with Mycoplasma gallisepticum and Mycoplasma synoviae.       1-2kg/ton feed

Storage

Store under dry conditions below 25ºC.

Expiry date is 2 (two) years after date of manufacture.

SIDE EFFECTS

Not established.

WITHDRAWAL PERIOD

For meat – 14 days after the last administration

Packing

25 kg bags: Inner lining is made of polyethylene; outer layer is made of 3-ply paper.